Dapoxetine for premature ejaculation
Take one tablet 1-3 hours before you have sex.
Precautions and Warnings
NHS doctors will also usually be able to write private prescriptions for dapoxetine (charges will apply). Authored 28 July 2020 by Dr A. Reviewed by Dr C. Pugh, Dr B. Babor Last reviewed 19 June 2023 Last updated 3 December 2025 Editorial policy Peer reviewed by Sid DajaniLast updated by Michael Stewart, MRPharmSLast updated 14 Apr 2025 Dapoxetine is prescribed for the treatment of premature ejaculation. The most common side-effects include feeling dizzy or faint, and feeling sick (nausea).
| Product | Dosage | Quantity + Bonus | Price | |
|---|---|---|---|---|
| Priligy Generic Dapoxetine | 60mg | 120 + 10 Pills | 341.26€ 325.01€ | |
| Cialis Original | 20mg | 22 + 2 Pills | 129.20€ 123.05€ | |
| Priligy Generic Dapoxetine | 60mg | 60 + 8 Pills | 183.06€ 174.34€ | |
| Priligy Generic Dapoxetine | 60mg | 90 + 10 Pills | 265.64€ 252.99€ | |
| Priligy Generic Dapoxetine | 60mg | 180 + 10 Pills | 494.76€ 471.20€ | |
| Priligy Generic Dapoxetine | 60mg | 30 + 6 Pills | 106.65€ 101.57€ | |
| Tadalista Super Active | 20mg | 10 Pills | 55.64€ 52.99€ | |
| Priligy Generic Dapoxetine | 60mg | 10 Pills | 47.63€ 45.36€ | |
| Cialis Original | 20mg | 34 + 2 Pills | 183.99€ 175.23€ | |
| Kamagra | 100mg | 120 + 6 Pills | 330.74€ 314.99€ | |
| Levitra Original | 20mg | 120 + 8 Pills | 528.19€ 503.04€ | |
| Priligy Generic Dapoxetine | 60mg | 20 + 4 Pills | 77.31€ 73.63€ |
Drinking a full glass of water at the same time as taking the tablet can reduce these effects.
- Priligy can be effective in improving sexual confidence.
- Combining therapy with counseling may yield better results.
- Do not take Priligy if you are allergic to dapoxetine.
- The medication is not a cure but manages symptoms of PE.
- It is only suitable for men with diagnosed premature ejaculation.
- Avoid heavy machinery or driving after taking Priligy.
- The medication should not be crushed or broken.
- Use with caution in combination with other prescribed drugs.
- Discuss possible interactions with your healthcare provider.
Premature ejaculation is the term used when a man orgasms (ejaculates) more quickly than he and/or his partner would like.
Safety advice
Patients with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency, or glucose-galactose malabsorption should not take dapoxetine (Priligy). Most men benefit from dapoxetine (Priligy), but psychological therapies and direct physical treatments can be used at the same time and may increase the benefit. Priligy was first launched in the UK in 2013 and remained under patent until October 2025, so only the drug company Menarini could produce and sell the medicine. When the patent expired, lower cost generic/unbranded versions became available and Menarini decided to no longer market Priligy. Dapoxetine is available on prescription in some NHS health authority areas, usually after specialist referral and advice - please check with your local GP surgery. For some men it can be temporary and can get better on its own; for others, prescribed treatments such as dapoxetine tablets can be helpful.
Side effects of Priligy Tablet
It is not intended to diagnose, treat, or replace professional medical or veterinary advice. Always consult your physician, pharmacist, or veterinarian regarding the safety, suitability, and proper use of any medication for yourself or your pet. How do I know if I have premature ejaculation? What treatment is available for premature ejaculation? Can I take erectile dysfunction drugs with dapoxetine (Priligy)?
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What are the side effects of dapoxetine (Priligy)? How can I reduce the risk of side effects of dapoxetine (Priligy)? Premature ejaculation (PE) is actually quite common. Up to 30% of men suffer with PE problems at some time in their life. It is usually related to stress and psychological factors rather than a physical problem.
Q. What is Priligy 60mg?
There are a variety of ways to help. Doctors define premature ejaculation as ejaculation in less than 2 minutes from penetration. However, if you ejaculate with very little stimulation, or before you want, and it is leading to relationship difficulties, you may benefit from treatment. There is medication available - dapoxetine (Priligy) - but there are also physical treatments such as extra thick condoms or anaesthetic (numbing) creams and sprays, and condoms pre-coated with numbing gel, which reduce penile sensitivity. These can be bought in many pharmacies without the need for a prescription. Dapoxetine is a selective serotonin reuptake inhibitor medicine which has been specially developed for the treatment of premature ejaculation.
Why Thousand Trusts Global Medship
Are allergic to dapoxetine or any of the other ingredients in Priligy Have a history of mania or severe depression Are taking monoamine oxidase inhibitors (MAOIs), thioridazine for treatment of schizophrenia, antidepressants, lithium, linezolid, tryptophan, St John's wort, tramadol, or migraine medications. If you are unsure whether you are taking any of these medications, ask your doctor. Before beginning treatment with Priligy, tell your doctor: If you take any medications, including all prescription and nonprescription medications, vitamins, and herbal supplements. If you have any medical conditions, including any other sexual disorders, low blood pressure, mental health problems, epilepsy, bleeding or blood clotting disorders, or kidney problems. Also tell your doctor if you use recreational drugs or if you have or are at risk of glaucoma.
Can I get Priligy on the NHS?
Males under the age of 18 years or older than 65 years old should not take Priligy. Priligy should not be taken by women. Do not drink grapefruit juice at least 24 hours prior to taking Priligy as this can increase the levels of the medication in your body. Avoid drinking alcohol while taking Priligy as consuming alcohol while taking Priligy can intensify dizziness, sleepiness, and slow reactions. Priligy can cause sleepiness, dizziness, fainting, trouble concentration, and blurred vision.
Tryptophan Metabolism & Dapoxetine Response (PubMed — PMID: 38511846)
Avoid driving or operating heavy machinery until you know how the medication affects you. Talk to your doctor before taking Priligy if you are lactose intolerant. If you develop side effects that are persistent or troublesome, immediately talk to your doctor. The most common side effects associated with taking Priligy include the following: dizziness, headache, feeling sick, mood changes, numb or tingling sensation, difficulty getting or keeping an erection, excessive sweating or flushing, diarrhea, constipation, stomach pain, bloating, sleep problems, strange dreams, tiredness, sleepiness, nasal congestion, high blood pressure, difficulty concentration, shaking or trembling, low desire to have sex, ringing in the ears, blurred vision, indigestion, and dry mouth. IMPORTANT NOTE: The information provided above is for general awareness and educational purposes only. It increases the time it takes to ejaculate and can improve the control over the ejaculation. It starts to work very quickly, so it is taken when you anticipate having sex, rather than every day. You have to take it 1-3 hours before you have sex. Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking dapoxetine it is important that your doctor knows: If you have a tendency to faint. If you have a tendency to faint.
- Priligy has been shown to improve interpersonal confidence.
- The medication should be part of a broader treatment plan.
- Rarely, Priligy can cause mood swings or confusion.
- Take Priligy at the same time before planned sexual activity.
- Discontinue use if you experience severe allergic reactions.
- Dapoxetine has a rapid clearance from the body.
- It is important to adhere strictly to dosing guidelines.
- Do not share your medication with others.
- Contact your healthcare provider if you notice unusual symptoms.
If you have a bleeding or clotting disorder. If you have ever had a mental health problem causing 'high' or 'low' moods, such as bipolar disorder, depression or mania.
- Schedule a medical assessment before starting Priligy.
- Follow dosing instructions precisely to avoid adverse effects.
- Report any severe side effects to your doctor immediately.
- Do not mix Priligy with other serotonergic drugs.
- Use only the prescribed dose for your condition.
- Avoid using Priligy with other medications for depression.
- The medication does not provide protection against STDs.
- Priligy has a quick onset, usually within 1 hour.
- Regular check-ups are recommended for long-term use.
If you have increased pressure in your eye, a condition called glaucoma.
Side Effects:
It is possible that grapefruit juice will cause the dapoxetine (Priligy) to stay in your system longer, so you should wait 24 hours after drinking grapefruit juice before taking dapoxetine. Grapefruit juice is a weak inhibitor of CYP3A4 gut wall metabolism, which can lead to a rise in levels of many drugs in your blood. Men usually get on well with dapoxetine (Priligy). The most common side effects are dizziness due to lower blood pressure, nausea, and headache. The full list of side effects is in the patient information leaflet.
Common side effects of Generic Priligy 30 mg
You are more likely to have side effects if taking alcohol, recreational drugs (such as LSD, heroin, methadone), or sleeping tablets at the same time buy generic priligy online as Priligy. There are some interactions with other drugs and some herbal remedies. The online consultation questionnaire checks if your medication is unsuitable to take with Priligy. Priligy is only licensed for use by men aged between 18 and 64 years. The effectiveness and safety of Priligy has not been established in patients aged 65 years and over. If you have any problems with the way your liver works, or if you have any problems with the way your kidneys work. If you have ever had an allergic reaction to a medicine. If you are taking any other medicines.
Severe Reactions (Seek Immediate Medical Help)
As premature ejaculation is often linked to stress and psychological factors, psychological therapies can help. See NHS - Ejaculation problems or the book Coping with Premature Ejaculation: How to Overcome PE, Please Your Partner, and Have Great Sex (2004) by Michael E. Metz. There are a few medical conditions where it would be unsafe to take Priligy. Checks are carried out within the Priligy online consultation.
Depression and anxiety
The license for dapoxetine states that Viagra (sildenafil), Cialis (tadalafil), and other erectile dysfunction drugs should not be used together with Priligy as there is a risk of very low blood pressure. If you suffer from both erectile dysfunction (ED) and premature ejaculation (PE) try treatment for ED first and if you still have PE problems discuss this with your regular doctor who may be able to prescribe these together following a more in depth review. Priligy (dapoxetine) was developed after it was realised that a side effect of taking SSRI antidepressants was to prolong erections. It was specifically designed as a short acting medication rather than an antidepressant but acts in the same way to increase serotonin levels in the brain, which delays ejaculation. It is washed out of the system within around 20 hours (half-life approximately 1.5 hours) and has no antidepressant effect.
Mode of application
There are two strengths of dapoxetine (Priligy) tablets: 30mg and 60mg. You should start with the lower 30mg strength, taking the tablet 1-3 hours before sexual intercourse. Swallow the tablet whole, with a full glass of water. The strength of tablet can be increased the next time, if the lower dose does not have the desired response and you had no significant side effects. You should not take a dose more than once every 24 hours and do not take it every day. This includes any medicines which are available to buy without a prescription, as well as herbal and complementary medicines.
- Priligy is effective in delaying ejaculation in many cases.
- It is not intended for use as a recreational drug.
- Follow your doctor’s advice on duration of treatment.
- Obtain a proper diagnosis before starting medication.
- Keep a record of your response to adjust dosing.
- Be cautious about combining with other medications.
- Wash hands before handling the tablets.
- Use the medication only as prescribed.
- Be aware of the possibility of withdrawal symptoms if stopped abruptly.
Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about dapoxetine, and will also provide you with a full list of the side-effects which you could experience from taking it.
| Country | Average Price (per tablet) | Insurance Coverage | Availability |
|---|---|---|---|
| USA | $10 - $15 | Varies | Widely available |
| UK | £8 - £12 | Some plans | Prescription required |
| Canada | CAD 12 - CAD 18 | Usually covered | Available at pharmacies |
Take dapoxetine exactly as your doctor tells you to. Drink a full glass of water at the same time as you take a tablet. The recommended starting dose is one 30 mg tablet, taken 1 to 3 hours before you anticipate having sex. Your doctor may later decide to increase your dose to one 60 mg tablet. Your doctor will only prescribe the higher dose for you if the 30 mg dose is insufficient, and providing you have not experienced any side-effects such as feeling faint.